Development of a coating skin protection measure based on synthetic hydrocolloids that protects against organic solvents, oils, lubricants, anhydrous paints/lacquers

The aim of this task was to develop a hydrophilic skin protection measure based on synthetic hydrocolloids. During the task, 35 preparations with various contents of hydrocolloids, emollients, emulgators, solvents and bacteriostatic substances were prepared. The use of the following substances was investigated: hydrocolloids (carbomethylcellulose and polyvinyl alcohol), emollients (glycerin and propylene glycol), solvents (distilled water and 96% ethyl alcohol) and various types of emulgators. Rewocid SB U-185, a bacteriostatic and fungistatic substance, was added. Elastic, non-sticky membranes were produced with 10% polyvinyl alcohol, 20% of glycerin as an emollient and 40% of ethyl alcohol. The addition of Carbopol Aqua SF-1, dextrin, collagen and polyquaternium 44 improved the elasticity and contact of the gel membrane with the skin.Tests were conducted to determine usability, barrier properties and efficacy of the developed preparations On the basis of further tests, it was established that the new gel did not contain microorganisms. Its properties were confirmed in tests of 35 volunteers. There was no allergic or toxic/irritating effect of human skin. When spread on the surface of the hand, the gel covers the skin with a uniform, smooth, non-sticky layer. It sticks to the skin of the hand well and dries in no longer than 180 s.The developed gel complies with the KOW/Z-14/04 criteria regarding safety and the protection of health for gels and hydrophilic creams that protect against anhydrous solvents and organic substances.